Systematic approaches to identify functional lncRNAs

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Systematic approaches to identify E3 ligase substrates

Protein ubiquitylation is a widespread post-translational modification, regulating cellular signalling with many outcomes, such as protein degradation, endocytosis, cell cycle progression, DNA repair and transcription. E3 ligases are a critical component of the ubiquitin proteasome system (UPS), determining the substrate specificity of the cascade by the covalent attachment of ubiquitin to subs...

متن کامل

Triangular Clique Based Multilevel Approaches to Identify Protein Functional Modules

Identifying functional modules is believed to reveal most cellular processes. There have been many computational approaches to investigate the underlying biological structures [1, 5, 10, 13]. A spectral clustering method plays a critical role identifying functional modules in a yeast protein-protein network in [10]. One of major obstacles clustering algorithms face and deal with is the limited ...

متن کامل

a review approaches to identify enteric bacterial pathogens

conclusions therefore, development of rapid diagnostic methods with suitable sensitivity and specificity is very important about this infectious disease. in this review, we will discuss some of the important diagnostic methods. context diarrhea is a common disease across the world. according to who, every year about two billion cases of diarrhea are reported in the world. it occurs mainly in th...

متن کامل

LncRNAs regulate cancer metastasis via binding to functional proteins

Cancer is one of the leading causes of death worldwide, and metastasis is a crucial characteristic of malignancy. Recent studies have shown that lncRNAs play an important role in regulating cancer metastasis through various molecular mechanisms. We briefly summarize four known molecular functions of lncRNAs, including their role as a signal, decoy, guide and scaffold. No matter which pattern ln...

متن کامل

Computational approaches to identify Leucine Zippers

The leucine zipper is a dimerization domain occurring mostly in regulatory and thus in many oncogenic proteins. The leucine repeat in the sequence has been traditionally used for identification, however with poor reliability. The coiled coil structure of a leucine zipper is required for dimerization and can be predicted with reasonable accuracy by existing algorithms. We exploit this fact for i...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Current Opinion in Genetics & Development

سال: 2016

ISSN: 0959-437X

DOI: 10.1016/j.gde.2015.12.005